Upon discovering Vault 81 and going through some quest lines(“Hole in the Wall”), you’ll get an annoying debuff - a minus ten (-10) to the health. Explained to you as a disease carried by and caught from a mole rat, you have to choose between curing yourself or Austin. Though the choice is created and made to carry some moral difficulty, you can bypass it with a simple trick. Just follow the guide. Upon obtaining the cure, get to the doctor, Jacob Forsythe. When he asks for the cure for Austin (him being sick from a mole bite) choose the option “Only one, it’s mine”. He’ll obviously try to play “You monster” card, just take a couple of steps back and drink the cure. He won’t freak out, so you can continue conversation like nothing happened -- choose the “You’re right” option and game will act as if you gave the cure to Forsythe. And that’s it. You’re free of the annoying minus ten (-10) buff, and the inhabitants of the Vault 81 won’t be mad at you for your “amoral” choice that might make.