Nonetheless, if you're walking into the unknown or simply haven't stopped by a save room in a while, go out of your way to find one. This will ensure that your progress is saved. If you don't do this, any item you acquired or experience you earned in between saves will be lost, which is truly a bummer. So, as with RPGs and other types of games, save often in Shadow Complex
Shadow complex remastered tip - Save With Regularity
Not saving in Shadow Complex is a difficult ordeal since the game's designers were pretty liberal with their placement of save rooms.